CHEMBL517167


SMILES CNCCN1CN(c2ccccc2)C2(CCN(Cc3c(Cl)cccc3Cl)CC2)C1=O
InChIKey FACAOOJHBRIGQV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 446.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.1 9.1 9.1 ChEMBL
δ OPRD Human Opioid A pKi 5.64 5.64 5.64 ChEMBL
κ OPRK Human Opioid A pKi 7.17 7.17 7.17 ChEMBL
μ OPRM Human Opioid A pKi 6.84 6.84 6.84 ChEMBL
NOP OPRX Human Opioid A pKi 9.1 9.1 9.1 PDSP Ki database
δ OPRD Human Opioid A pKi 5.64 5.64 5.64 PDSP Ki database
κ OPRK Human Opioid A pKi 7.17 7.17 7.17 PDSP Ki database
μ OPRM Human Opioid A pKi 6.84 6.84 6.84 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database