CHEMBL517265


SMILES O=C1N(CCNC2CC2)CN(c2ccccc2)C12CCN(C(c1ccccc1Cl)c1ccccc1Cl)CC2
InChIKey PHEIVMXYEVVNHK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 548.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.43 8.43 8.43 ChEMBL
δ OPRD Human Opioid A pKi 5.95 5.95 5.95 ChEMBL
κ OPRK Human Opioid A pKi 5.99 5.99 5.99 ChEMBL
μ OPRM Human Opioid A pKi 6.01 6.01 6.01 ChEMBL
δ OPRD Human Opioid A pKi 5.94 5.94 5.94 PDSP Ki database
κ OPRK Human Opioid A pKi 5.99 5.99 5.99 PDSP Ki database
μ OPRM Human Opioid A pKi 6.01 6.01 6.01 PDSP Ki database
NOP OPRX Human Opioid A pKi 8.43 8.43 8.43 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database