CHEMBL51767


SMILES COc1ccccc1N1CCN(CCCOc2ccc3c(C)cc(=O)oc3c2)CC1
InChIKey WYYRWPAVRAAIOL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 408.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Rat Adrenoceptors A pKd 9.07 9.07 9.07 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.93 7.93 7.93 ChEMBL
α1A ADA1A Human Adrenoceptors A pKd 9.07 9.07 9.07 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.76 6.76 6.76 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.93 7.93 7.93 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database