CHEMBL5182877


SMILES COc1ccccc1N1CCN(CCCN2CCN(c3ncccc3C#N)CC2)CC1
InChIKey AMUCTWAVRKDCJA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 420.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.57 5.57 5.57 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.64 4.64 4.64 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.75 7.75 7.75 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.96 6.96 6.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database