CHEMBL5183389


SMILES NC(=O)c1ccc(F)c2c1CC(N(C1CCC1)C1CCC1)CO2
InChIKey MQTUXRKNJYPMCG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 318.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.22 9.22 9.22 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.0 6.0 6.0 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
H2 HRH2 Guinea pig Histamine A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.23 9.23 9.23 PDSP Ki database
H1 HRH1 Rat Histamine A pKi 5.0 5.0 5.0 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 6.0 6.0 6.0 PDSP Ki database
β2 ADRB2 Rat Adrenoceptors A pKi 6.47 6.47 6.47 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 5.72 5.72 5.72 PDSP Ki database
5-HT6 5HT6R Rat 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database