CHEMBL5190788


SMILES N#Cc1cccnc1N1CCN(CCCN2CCN(c3cccc(Cl)c3Cl)CC2)CC1
InChIKey RTVQLAGHMGMPSS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 458.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.24 6.24 6.24 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.33 6.33 6.33 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.0 8.0 8.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database