CHEMBL5193103


SMILES O=c1n(CCCCCCN2CCN(c3cccc(C(F)(F)F)c3)CC2)nc2ccccn12
InChIKey HPCHKTZCFMXPGM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 447.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.97 5.97 5.97 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.39 6.39 6.39 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.54 6.54 6.54 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.77 7.77 7.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.21 7.21 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database