CHEMBL5199820


SMILES Nc1nc(NCCc2c[nH]c3ccccc23)nc(NCCN2CCN(c3ccccc3)CC2)n1
InChIKey URSQASKSKBUBLK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 4
Rotatable bonds 9
Molecular weight (Da) 457.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.1 8.1 8.1 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.17 7.17 7.17 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.39 6.39 6.39 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.38 6.38 6.38 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.56 6.56 6.56 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database