CHEMBL582877


SMILES CC1(C)N=C(N)N=C(Nc2cccc(Br)c2)N1
InChIKey ODCAEXNEGXTNBY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 1
Molecular weight (Da) 295.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.41 6.41 6.41 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.82 5.82 5.82 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.58 5.58 5.58 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.68 5.68 5.68 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.16 6.16 6.16 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.69 7.69 7.69 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.58 6.58 6.58 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.11 6.11 6.11 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.18 6.18 6.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 6.49 6.49 6.49 ChEMBL