CHEMBL5201719


SMILES Nc1nc(NCCc2c[nH]c3ccccc23)nc(N2CCN(c3cccc(Cl)c3Cl)CC2)n1
InChIKey KMXCBWFCHIVUJL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 482.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.78 5.78 5.78 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.75 5.75 5.75 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.1 5.1 5.1 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.17 5.17 5.17 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.49 5.49 5.49 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database