CHEMBL5202054


SMILES O=c1n(CCCCCCN2CCN(c3cccc(Cl)c3)CC2)nc2ccccn12
InChIKey VUHBOMDUPLECSX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 413.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.56 6.56 6.56 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.71 5.71 5.71 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.86 6.86 6.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database