CHEMBL522151


SMILES c1ccc(-c2cccc3c2OC(C2=NCCN2)CO3)cc1
InChIKey LOGUSYSMQQMCJG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 280.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.32 6.32 6.32 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.16 6.16 6.16 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.62 6.62 6.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 4.65 4.65 4.65 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 5.5 5.5 5.5 ChEMBL