CHEMBL522194


SMILES COc1ccccc1N1CCN(CCCCCC(=O)NCc2ccc(OS(C)(=O)=O)cc2)CC1
InChIKey NQNRCHXTCUMIPZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 489.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.15 7.15 7.15 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.54 7.54 7.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.04 7.04 7.04 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.15 7.15 7.15 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.54 7.54 7.54 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.04 7.04 7.04 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database