CHEMBL522343


SMILES CC(C)c1ccccc1N1CCN(CCCCCC(=O)NCc2ccncc2)CC1
InChIKey MNZXUJMLYMHIPK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 408.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.29 8.29 8.29 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.49 6.49 6.49 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.68 7.68 7.68 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.49 6.49 6.49 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.68 7.68 7.68 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.29 8.29 8.29 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database