CHEMBL53416


SMILES c1ccc(CN2CCN(c3nc4ccccc4n4cccc34)CC2)cc1
InChIKey PADMFNVKWGURLR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 342.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Bovine 5-Hydroxytryptamine A pIC50 4.98 4.98 4.98 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 4.89 4.89 4.89 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 5.61 5.61 5.61 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 5.59 5.59 5.59 ChEMBL