CHEMBL56620


SMILES O=C1CC2(CCCC2)C(=O)N1CCN1CCN(c2cc(Cl)ccc2Cl)CC1
InChIKey PBOALASTYPPBPW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 409.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 8.51 8.51 8.51 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.08 7.08 7.08 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 7.17 7.17 7.17 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.26 7.26 7.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database