N-methylhistamine


SMILES Cn1cc(nc1)CCN
InChIKey FHQDWPCFSJMNCT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 125.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKi 5.0 7.64 9.3 PDSP Ki database
H3 HRH3 Human Histamine A pKi 4.7 4.7 4.7 ChEMBL
H3 HRH3 Human Histamine A pKd 9.1 9.1 9.1 Guide to Pharmacology
H3 HRH3 Human Histamine A pKi 8.6 8.95 9.3 Guide to Pharmacology
H4 HRH4 Human Histamine A pKi 7.64 7.64 7.64 PDSP Ki database
H4 HRH4 Human Histamine A pKi 4.96 4.96 4.96 ChEMBL
H4 HRH4 Human Histamine A pKd 7.8 7.8 7.8 Guide to Pharmacology
H4 HRH4 Human Histamine A pKi 7.3 7.45 7.6 Guide to Pharmacology
H4 HRH4 Mouse Histamine A pKi 6.5 6.5 6.5 Guide to Pharmacology
H4 HRH4 Rat Histamine A pKi 6.3 6.3 6.3 Guide to Pharmacology
H3 HRH3 Rat Histamine A pKi 8.82 8.87 8.92 PDSP Ki database
H3 HRH3 Rat Histamine A pKd 9.1 9.1 9.1 Guide to Pharmacology
H3 HRH3 Rat Histamine A pKi 8.8 8.8 8.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TSH TSHR Human Glycoprotein hormone A Potency 5.2 5.2 5.2 ChEMBL