CHEMBL69717


SMILES O=C1c2ccccc2C(=O)N1CCCCN1CCN(c2cccc(Cl)c2Cl)CC1
InChIKey SGVBRIHFEULKBC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 431.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.32 8.32 8.32 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.99 6.99 6.99 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.43 6.43 6.43 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.39 8.39 8.39 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.92 6.92 6.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database