CHEMBL69943


SMILES CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)C1CCc2ccc3[nH]ccc3c2C1
InChIKey GMWZSACWHHMURD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 423.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.54 7.54 7.54 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.65 6.65 6.65 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 7.58 7.58 7.58 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.82 7.82 7.82 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.72 8.72 8.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database