CHEMBL569513


SMILES O=c1[nH]c2cccc(N3CCN(CC4CCc5[nH]c6ccc(F)cc6c5C4)CC3)c2o1
InChIKey ZEIYGHCLSNJBKD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 420.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.17 6.17 6.17 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.89 6.89 6.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.22 7.49 7.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.22 7.49 7.77 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.89 6.89 6.89 PDSP Ki database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.17 6.17 6.17 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database