CHEMBL570973


SMILES C=CCc1ccccc1C(C)OC1=NCCN1
InChIKey MCAGSCISRRGDGQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 230.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.47 6.47 6.47 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.07 7.07 7.07 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.24 7.24 7.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 6.0 6.0 6.0 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 7.3 7.3 7.3 ChEMBL