CHEMBL57176


SMILES C#Cc1c[nH]c(CN2CCN(c3ccccc3)CC2)c1
InChIKey VOPNYIHLMCVSPL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 265.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 ChEMBL
D1 DRD1 Bovine Dopamine A pKi 5.7 5.7 5.7 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.23 8.23 8.23 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.07 6.07 6.07 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.11 6.18 6.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 8.72 8.72 8.72 ChEMBL