CHEMBL78785


SMILES COc1ccccc1N1CCN(CCCNc2cc(-c3ccccc3)nn(C)c2=O)CC1
InChIKey OKNLSDNUZNHITO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 433.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.9 6.9 6.9 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.59 8.59 8.59 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 8.26 8.26 8.26 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.93 7.93 7.93 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database