CHEMBL81649


SMILES NS(=O)(=O)c1ccc(N2CCN(CC[C@H]3OCCc4ccccc43)CC2)cc1
InChIKey WNUQCGWXPNGORO-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 401.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.0 7.0 7.0 ChEMBL
D3 DRD3 Rat Dopamine A pKi 5.54 5.54 5.54 ChEMBL
D2 DRD2 Rat Dopamine A pKi 5.25 5.25 5.25 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.62 5.62 5.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database