CHEMBL584046


SMILES CN(C)CCn1cc(S(=O)(=O)c2cccc(Cl)c2)c2cccnc21
InChIKey QFJMKWALUAWNKC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 363.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.64 8.64 8.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.92 5.92 5.92 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pEC50 7.82 7.82 7.82 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 6.32 6.32 6.32 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.88 6.88 6.88 ChEMBL