CHEMBL87717


SMILES O=C(c1ccc(F)cc1)C1CCN(CCC2Cc3ccccc3C2=O)CC1
InChIKey AVNSTIVMFUJDDN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 365.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 5.55 5.55 5.55 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.15 7.15 7.15 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.78 6.78 6.78 ChEMBL
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 6.43 6.43 6.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database