ArrestinDb

CHEMBL70565

Agent/drug
Bioactivity

CHEMBL70565

SMILES	CCCN1CCO[C@@H]2c3cc(O)ccc3OC[C@H]21
InChIKey	YOILXOMTHPUMRG-TZMCWYRMSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	2
Molecular weight (Da)	249.1

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	7CMV

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

μ	OPRM	Human	Opioid	A	pKi	4.44	4.44	4.44	ChEMBL
5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	5.78	5.78	5.78	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	5.93	7.18	7.69	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	7.11	8.52	8.85	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	6.77	7.17	7.58	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Rat	Dopamine	A	pIC50	5.51	6.21	6.91	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pEC50	8.24	8.24	8.24	ChEMBL
D₃	DRD3	Rat	Dopamine	A	pEC50	9.44	9.44	9.44	ChEMBL
M₁	ACM1	Rat	Acetylcholine (muscarinic)	A	Potency	5.15	6.77	7.75	ChEMBL
NPS	NPSR1	Human	Neuropeptide S	A	Potency	4.90	5.75	6.60	ChEMBL
TSH	TSHR	Human	Glycoprotein hormone	A	Potency	5.30	5.30	5.30	ChEMBL

Showing 1 to 6 of 6 entries

CHEMBL70565

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	7CMV

Compound is not listed as a drug.