ArrestinDb

CHEMBL73538

Agent/drug
Bioactivity

CHEMBL73538

SMILES	CN1CCN(C2=Nc3ccccc3Nc3ccccc32)CC1
InChIKey	VQHITFFJBFOMBG-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	0
Molecular weight (Da)	292.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	8E9W 8E9X

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_2C	5HT2C	Rat	5-Hydroxytryptamine	A	pKi	7.08	7.08	7.08	ChEMBL
D₁	DRD1	Rat	Dopamine	A	pKi	6.70	6.70	6.70	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	5.60	5.60	5.60	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	6.38	6.38	6.38	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₁	DRD1	Rat	Dopamine	A	pIC50	6.05	6.05	6.05	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL73538

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	8E9W 8E9X

Compound is not listed as a drug.