CORYNANRHEIDINE


SMILES CC[C@@H]1CN2CCc3c([nH]c4ccccc34)[C@@H]2C[C@@H]1/C(=C\OC)C(=O)OC
InChIKey NMLUOJBSAYAYEM-QALMDFCDSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 368.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Human Adrenoceptors A pKi 7.38 7.38 7.38 ChEMBL
δ OPRD Human Opioid A pKi 5.54 5.54 5.54 ChEMBL
κ OPRK Human Opioid A pKi 5.72 5.72 5.72 ChEMBL
μ OPRM Human Opioid A pKi 5.72 6.32 6.93 ChEMBL
κ OPRK Guinea pig Opioid A pKi 5.59 5.59 5.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database