CHEMBL61231


SMILES CCOC(=O)N1CCN(CCCOc2ccc(C(=O)CC(C)C)cc2)CC1
InChIKey LESFXMYDPQCDFJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 376.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 8.14 8.14 8.14 ChEMBL
H2 HRH2 Human Histamine A pKi 4.16 4.16 4.16 ChEMBL
H1 HRH1 Human Histamine A pKi 6.03 6.03 6.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database