CHEMBL62829


SMILES Fc1cccc(-c2cccc(CN3CCN(c4ncccn4)CC3)c2)c1
InChIKey HSIMYBORWJJPOY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 348.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 8.05 8.23 8.4 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 6.52 6.52 6.52 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.7 6.7 6.7 ChEMBL
D2 DRD2 Human Dopamine A pIC50 7.09 7.09 7.09 ChEMBL