(+)-trans-H2-PAT


SMILES CN([C@@H]1Cc2ccccc2[C@H](C1)c1ccccc1)C
InChIKey DXJUCAUQIHNOAF-SJLPKXTDSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 251.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations 5-HT2C H1

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.03 7.03 7.03 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.52 7.52 7.52 ChEMBL
H1 HRH1 Human Histamine A pKi 7.4 7.97 8.6 Guide to Pharmacology
H3 HRH3 Human Histamine A pKi 8.7 8.7 8.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database