CHEMBL67381


SMILES O=C1Nc2cccnc2N(C(=O)CN2CCN(Cc3ccccc3)CC2)c2ccccc21
InChIKey RJGGRENGKYTGDC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 427.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Rat Acetylcholine (muscarinic) A pKi 6.66 6.66 6.66 ChEMBL
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 6.62 6.62 6.62 ChEMBL
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 6.62 6.62 6.62 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 6.48 6.48 6.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database