CHEMBL70003


SMILES CC(=O)NCCN1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1
InChIKey VQDPSXHKOQSFTH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 422.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Rat Acetylcholine (muscarinic) A pKi 5.59 5.59 5.59 ChEMBL
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 6.01 6.01 6.01 ChEMBL
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 5.6 5.6 5.6 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 6.17 6.17 6.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database