CHEMBL74756


SMILES O=C(c1ccc(F)cc1)C1CCN(CCc2ccccc2I)CC1
InChIKey JREBTSVEMYTHEU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 437.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.43 8.43 8.43 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.89 8.89 8.89 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.86 6.86 6.86 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.45 7.45 7.45 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.71 8.71 8.71 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database