FAUC 113


SMILES Clc1ccc(N2CCN(Cc3cnn4ccccc34)CC2)cc1
InChIKey XVPRVMIFXXOEFR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 326.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 ChEMBL
D4 DRD4 Rat Dopamine A pKi 8.51 8.55 8.59 ChEMBL
D1 DRD1 Pig Dopamine A pKi 4.92 5.23 5.55 ChEMBL
D1 DRD1 Bovine Dopamine A pKi 4.92 4.92 4.92 ChEMBL
D2 DRD2 Bovine Dopamine A pKi 5.33 5.33 5.33 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.44 8.52 8.7 ChEMBL
D1 DRD1 Human Dopamine A pKi 4.92 4.92 4.92 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.3 5.31 5.41 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.85 5.85 5.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.37 5.48 5.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 7.8 7.86 7.92 ChEMBL