CHEMBL81330


SMILES Fc1ccc(N2CCN(CCC3OCCc4ccccc43)CC2)cc1
InChIKey UKOCGOXTVCIACM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 340.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.52 8.52 8.52 ChEMBL
D1 DRD1 Rat Dopamine A pKi 6.39 6.39 6.39 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.8 6.8 6.8 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.52 8.52 8.52 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.92 6.92 6.92 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.39 6.39 6.39 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.16 7.16 7.16 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.62 6.62 6.62 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.24 8.24 8.24 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.87 6.87 6.87 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.7 6.7 6.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database