L-366,811


SMILES CCC(C)C(C(=O)N(C(CC1=CNC2=CC=CC=C21)C=O)C(=O)C3CCCN3C(=O)C(CC4=CC=CCC4(C(=O)N5CCNCC5)C(=O)N6CC=CC=C6)NC)N
InChIKey PQTORSHXODXZHK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 4
Rotatable bonds 14
Molecular weight (Da) 780.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OT OXYR Rat Vasopressin and oxytocin A pKi 8.38 8.43 8.47 PDSP Ki database
OT OXYR Human Vasopressin and oxytocin A pKi 8.35 8.35 8.35 PDSP Ki database
OT OXYR Rhesus macaque Vasopressin and oxytocin A pKi 8.33 8.33 8.33 PDSP Ki database
V2 V2R Rat Vasopressin and oxytocin A pKi 6.62 6.62 6.62 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database