YM348


SMILES CCC1=CC2=C(O1)C=CC3=C2N(N=C3)CC(C)N
InChIKey QLOOWOVVZLBYHU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 243.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 9.05 9.05 9.05 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.89 6.89 6.89 PDSP Ki database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 PDSP Ki database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.6 8.6 8.6 PDSP Ki database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.75 6.75 6.75 PDSP Ki database
α2A ADA2A Human Adrenoceptors A pKi 6.9 6.9 6.9 PDSP Ki database
5-HT1D F1MMU1 Bovine 5-Hydroxytryptamine A pKi 6.32 6.32 6.32 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database