2-(2-chlorophenyl)-1-(4-chlorophenyl)-5-ethyl-N-((1S,2S)-2-hydroxycyclohexyl)-1H-imidazole-4-carboxamide


SMILES CCC1=C(N=C(N1C2=CC=C(C=C2)Cl)C3=CC=CC=C3Cl)C(=O)NC4CCCCC4O
InChIKey WMNURCXVCQHWLM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 457.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 8.3 8.3 8.3 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 5.64 5.64 5.64 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database