(3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-2-yl)propylamino)methyl)-7,9-dihydro-2H-[1,4]dioxino[2,3-e]indol-8(3H)-one


SMILES C1CC2=C(CC1CCCNCC3COC4=C(O3)C=CC5=C4CC(=O)N5)NC6=C2C=C(C=C6)F
InChIKey OTCAUALNGZOKLN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 449.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.22 8.22 8.22 PDSP Ki database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.21 6.3 6.4 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.3 7.32 7.35 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database