CHEMBL322610


SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
InChIKey OBADRSUMIBIHEX-FKWFRFQNSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC3 MC3R Mouse Melanocortin A pKd 7.25 7.33 7.41 ChEMBL
MC3 MC3R Mouse Melanocortin A pKi 6.58 6.92 7.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pEC50 8.13 8.46 8.8 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 7.22 7.3 7.39 ChEMBL
MC4 MC4R Mouse Melanocortin A pEC50 7.6 8.0 8.4 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 7.28 8.09 8.9 ChEMBL