ArrestinDb

Methadone,(R)(-)

Agent/drug
Bioactivity

Methadone,(R)(-)

SMILES	CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1
InChIKey	USSIQXCVUWKGNF-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	0
Rotatable bonds	7
Molecular weight (Da)	309.2

Database connections

PubChem ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

No bioactivity data available.

Methadone,(R)(-)

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 4

Phase III 4

Approved Yes

Database connections

PubChem ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease				Phase

Gene	Protein	Receptor family	Ligand type	Class	Indication name	ICD11	ATC	Association score	Phase	Approved

OPRD	δ receptor	Opioid receptors	Peptide receptors	Class A	Chronic pain, unspecified	MG30.Z		0.586	3	Yes
OPRD	δ receptor	Opioid receptors	Peptide receptors	Class A	Cocaine dependence, unspecified	6C45.2Z		0.347	3	Yes
OPRD	δ receptor	Opioid receptors	Peptide receptors	Class A	Disorders due to use of opioids, unspecified	6C43.Z		0.580	4	Yes
OPRD	δ receptor	Opioid receptors	Peptide receptors	Class A	Neonatal withdrawal syndrome from maternal use of drugs of addiction	KD35		0.007	2	Yes
OPRD	δ receptor	Opioid receptors	Peptide receptors	Class A	Opioid dependence, unspecified	6C43.2Z		0.493	4	Yes
OPRD	δ receptor	Opioid receptors	Peptide receptors	Class A	Pain, unspecified	MG3Z		0.608	4	Yes
OPRD	δ receptor	Opioid receptors	Peptide receptors	Class A	Restless legs syndrome	7A80		0.259	2	Yes
OPRD	δ receptor	Opioid receptors	Peptide receptors	Class A	Unknown or unspecified psychoactive substance dependence, substance and state of remission unspecified	6C4G.2Z		0.600	4	Yes
OPRM	μ receptor	Opioid receptors	Peptide receptors	Class A	Chronic pain, unspecified	MG30.Z		0.607	3	Yes
OPRM	μ receptor	Opioid receptors	Peptide receptors	Class A	Cocaine dependence, unspecified	6C45.2Z		0.391	3	Yes
OPRM	μ receptor	Opioid receptors	Peptide receptors	Class A	Disorders due to use of opioids, unspecified	6C43.Z		0.681	4	Yes
OPRM	μ receptor	Opioid receptors	Peptide receptors	Class A	Neonatal withdrawal syndrome from maternal use of drugs of addiction	KD35		0.583	2	Yes
OPRM	μ receptor	Opioid receptors	Peptide receptors	Class A	Opioid dependence, unspecified	6C43.2Z		0.523	4	Yes
OPRM	μ receptor	Opioid receptors	Peptide receptors	Class A	Pain, unspecified	MG3Z		0.609	4	Yes
OPRM	μ receptor	Opioid receptors	Peptide receptors	Class A	Restless legs syndrome	7A80		0.471	2	Yes
OPRM	μ receptor	Opioid receptors	Peptide receptors	Class A	Unknown or unspecified psychoactive substance dependence, substance and state of remission unspecified	6C4G.2Z		0.614	4	Yes

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