CLOSANTEL


SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O
InChIKey JMPFSEBWVLAJKM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 661.9

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pKi 6.0 6.0 6.0 ChEMBL
A3 AA3R Human Adenosine A pKi 7.27 7.27 7.27 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 6.08 6.08 6.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pIC50 5.15 5.15 5.15 ChEMBL
A3 AA3R Human Adenosine A pIC50 7.02 7.02 7.02 ChEMBL
α2B ADA2B Human Adrenoceptors A pIC50 5.75 5.75 5.75 ChEMBL