ArrestinDb

acamprosate

Agent/drug
Bioactivity

acamprosate

SMILES	CC(=O)NCCCS(=O)(=O)O
InChIKey	AFCGFAGUEYAMAO-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	4
Molecular weight (Da)	181.2

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

No bioactivity data available.

acamprosate

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 6

Phase II 8

Phase III 0

Approved Yes

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease				Phase

Gene	Protein	Receptor family	Ligand type	Class	Indication name	ICD11	ATC	Association score	Phase	Approved

GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Alcohol dependence, unspecified	6C40.2Z	N07B	0.572	4	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Autism spectrum disorder, unspecified	6A02.Z	N07B	0.161	1	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Cocaine dependence, unspecified	6C45.2Z	N07B	0.101	2	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Feeding or eating disorders, unspecified	6B8Z	N07B	0.092	2	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Fragile X chromosome	LD55	N07B	0.362	2	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Stimulant dependence including amphetamines, methamphetamine or methcathinone, unspecified	6C46.2Z	N07B	0.010	2	Yes
GABR1	GABA_B1	GABA_B receptors	Amino acid receptors	Class C	Tinnitus	MC41	N07B	0.005	1	Yes
GRM5	mGlu₅ receptor	Metabotropic glutamate receptors	Amino acid receptors	Class C	Alcohol dependence, unspecified	6C40.2Z	N07B	0.025	4	Yes
GRM5	mGlu₅ receptor	Metabotropic glutamate receptors	Amino acid receptors	Class C	Autism spectrum disorder, unspecified	6A02.Z	N07B	0.179	1	Yes
GRM5	mGlu₅ receptor	Metabotropic glutamate receptors	Amino acid receptors	Class C	Cocaine dependence, unspecified	6C45.2Z	N07B	0.078	2	Yes
GRM5	mGlu₅ receptor	Metabotropic glutamate receptors	Amino acid receptors	Class C	Feeding or eating disorders, unspecified	6B8Z	N07B	0.013	2	Yes
GRM5	mGlu₅ receptor	Metabotropic glutamate receptors	Amino acid receptors	Class C	Fragile X chromosome	LD55	N07B	0.141	2	Yes
GRM5	mGlu₅ receptor	Metabotropic glutamate receptors	Amino acid receptors	Class C	Tinnitus	MC41	N07B	0.005	1	Yes

Showing 1 to 13 of 13 entries