L-750,667


SMILES Ic1ccc(cc1)N1CCN(CC1)Cc1c[nH]c2c1cccn2
InChIKey OOEUHRGMLFVKQO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 418.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations D4

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 9.29 9.29 9.29 ChEMBL
D4 DRD4 Rat Dopamine A pKi 10.0 10.0 10.0 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TSH TSHR Human Glycoprotein hormone A Potency 4.6 4.6 4.6 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.8 4.82 4.85 ChEMBL