ArrestinDb

loxiglumide

Agent/drug
Bioactivity

loxiglumide

SMILES	CCCCCN(CCCOC)C(=O)C(CCC(=O)O)NC(=O)c1ccc(Cl)c(Cl)c1
InChIKey	QNQZBKQEIFTHFZ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	14
Molecular weight (Da)	460.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids Drug Central GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CCK₂	GASR	Rat	Cholecystokinin	A	pKi	5.00	6.02	6.57	PDSP Ki database

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CCK₁	CCKAR	Rat	Cholecystokinin	A	pIC50	6.50	6.50	6.50	Guide to Pharmacology
CCK₁	CCKAR	Human	Cholecystokinin	A	pIC50	6.71	6.71	6.71	ChEMBL
CCK₁	CCKAR	Human	Cholecystokinin	A	pIC50	8.17	8.17	8.17	Drug Central
CCK₁	CCKAR	Rat	Cholecystokinin	A	pIC50	8.19	8.19	8.19	Drug Central

Showing 1 to 4 of 4 entries

loxiglumide

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids Drug Central GPCRdb

Compound is not listed as a drug.