ArrestinDb

LTB₄

LTB₄

SMILES	CCCCC/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(=O)O
InChIKey	VNYSSYRCGWBHLG-AMOLWHMGSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	3
Rotatable bonds	14
Molecular weight (Da)	336.2

Database connections

Guide To Pharmacology DrugBank ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	7VKT

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

BLT₁	LT4R1	Human	Leukotriene	A	pKi	8.54	9.29	9.92	ChEMBL
BLT₁	LT4R1	Human	Leukotriene	A	pKi	9.40	9.40	9.40	Guide to Pharmacology
BLT₂	LT4R2	Human	Leukotriene	A	pKd	7.64	7.64	7.64	Guide to Pharmacology

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

BLT₁	LT4R1	Human	Leukotriene	A	pIC50	7.50	8.31	8.72	ChEMBL
BLT₂	LT4R2	Human	Leukotriene	A	pIC50	7.60	7.60	7.60	Guide to Pharmacology
BLT₂	LT4R2	Human	Leukotriene	A	pEC50	6.85	6.85	6.85	Guide to Pharmacology

Showing 1 to 3 of 3 entries

LTB₄

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Endogenous
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

Guide To Pharmacology DrugBank ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	7VKT

Compound is not listed as a drug.

This ligand is endogenous.