CHEMBL125745


SMILES NCCc1cccc2c1ccn2S(=O)(=O)c1ccccc1
InChIKey VNWSJGQXBGKBED-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 300.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 7.33 7.33 7.33 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 8.19 8.19 8.19 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.35 8.35 8.35 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.54 7.54 7.54 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.62 8.62 8.62 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.03 6.03 6.03 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.85 6.85 6.85 ChEMBL
5-HT5A 5HT5A Rat 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database