CHEMBL1276218


SMILES CC(Oc1ccccc1C1CC1)C1=NCCN1
InChIKey QYCJTZDZQXSXSC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 230.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.51 6.51 6.51 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.1 7.1 7.1 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.64 7.64 7.64 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.14 8.14 8.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 5.5 5.5 5.5 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 7.4 7.4 7.4 ChEMBL